Juan Carlos Muñoz García

In 2009, I received a PhD scholarship from CSIC to conduct my doctoral research at the Instituto de Investigaciones Químicas (IIQ, CSIC–University of Seville), focusing on the atomic‑scale characterization of heparin‑like oligosaccharides and their interactions with proteins through ligand‑observed NMR and molecular modelling techniques (Muñoz-García et al. J. Am. Chem. Soc. 2015; Muñoz-García et al. Chem. Eur. J. 2012). I completed short research stays in top laboratories (Prof. Robert Woods, Univ. of Georgia, 2011; Dr. Anne Imberty, CERMAV, 2012). In 2013, I graduated with a PhD in Chemistry with International Mention, awarded cum laude.

In 2013, I joined Prof. Anthony Watts at (Dept. Biochem., Univ. of Oxford) as a Research Associate, funded by UCB Celltech. Here, I led studies on the structure, dimerization, and lipid interactions of the GPCRs Neurotensin Receptor 1 and Dopamine Receptor 1 through homology modeling, MD simulations, and Electronic Paramagnetic Resonance data (Dijkman et al. Nat. Comm. 2018; Dijkman, Muñoz-García et al. Sci. Adv. 2020)

In 2016, I joined Prof. Yaroslav Khimyak’s group (School of Pharmacy, Univ. of East Anglia) as a Senior Research Associate, where I developed solution, HR‑MAS, and solid‑state NMR methods for probing the structure and dynamics of carbohydrate‑based gels (Gabrielli et al. J. Colloid Interface Sci. 2021; Muñoz-García et al. Biomacromolecules 2019; Calabrese, Muñoz-García et al. J. Colloid Interface Sci. 2019).

In 2022, I was awarded a Marie Skłodowska-Curie Postdoctoral Fellowship to return to IIQ. Here, my work has been acknowledged with the Young Scientist Award 2024 from Journal of Magnetic Resonance. In 2024, I was awarded an EMERGIA contract and research grant from the Junta de Andalucía. In Jan 2026, I started a permanent Tenured Scientist position at IIQ. Since my return to IIQ, I have led the development of chemoinformatics and NMR‑integrated software —RedMat (redmat.iiq.us‑csic.es) and RedDat (stdrdweb.streamlit.app)— (Nepravishta et al. J. Med. Chem. 2024; Rocha et al. Anal. Chem. 2024), as well as ML-boosted computational methods to accelerate the structural validation of protein–fragment complexes (Nepravishta, Muñoz-García et al. J. Am. Chem. Soc. 2025). Also, I develop solution NMR protocols to monitor solvent-gelator interactions responsible of gel formation, e.g. biopolymer and MOF gels (Muñoz-García et al. Angew. Chem. Int. Ed. 2025).